教員情報 - 栗山　磯子 | 兵庫大学　兵庫大学短期大学部　

クリヤマ　イソコ Isoko Kuriyama
栗山　磯子

所属兵庫大学健康科学部栄養学科

職種講師

著書・論文歴
著書	決定版　阻害剤・活性化剤ハンドブック (共著) 2019/09
著書	食品学Ⅰ (共著) 2015/11
論文	管理栄養士の職域に特化した授業形態が学生の能力向上や行動変容に与える影響兵庫大学論集 (32) (共著) 2026/03/31
論文	管理栄養士養成における3コース制教育の学習効果とキャリア形成への寄与兵庫大学論集 (32) (共著) 2026/03/31
論文	製パン工程がガジュツ（Curcuma zedoaria）のマルターゼ阻害活性と3T3-L1 細胞に対する分化促進作用に及ぼす影響日本調理科学会誌 59 (1),1-7頁 (共著) 2026/02
論文	職域毎の選択制コース別授業は、管理栄養士業務内容の理解を深める兵庫大学論集 (共著) 2025/03
論文	管理栄養士養成課程学生のニーズに応じた職域毎の授業形態が学習意欲に及ぼす影響兵庫大学論集 (29),147-160頁 (共著) 2023/03/20
論文	Curcuma zedoaria 50% methanol extracts increase adiponectin secretion by enhancing PPAR γmRNA expression in 3T3-L1 cells Bioscience, Biotechnology, and Biochemistry 86 (9),1295-1299頁 (共著) 2022/06/24
論文	東播磨地域産にんにくの糖質分解酵素阻害活性兵庫大学論集 (27・28),75-80頁 (共著) 2022/02/28
論文	管理栄養士の職域に特化した授業形態が学生の意識や学習意欲に与える影響兵庫大学論集 (26),225-236頁 (共著) 2021/03/19
論文	東播磨地域産農作物における糖質分解酵素阻害活性の探索兵庫大学論集 (26),133-140頁 (共著) 2021/03/19
論文	希望職種に特化した授業形態は管理栄養士を目指す学生の意識を向上させるのに有効である兵庫大学論集 25,85-93頁 (共著) 2020
論文	Influence of particle size on the in vitro and in vivoanti-inflammatory and anti-allergic activities of a curcumin lipid nanoemulsion. Int J Mol Med. 35(6):1720-8. (共著) 2015/06
論文	Bioactive dihydronaphthoquinone derivatives from Fusarium solani. J Nat Prod. 77(9):1992-6. (共著) 2014/09
論文	Inhibition of Mammalian DNA Polymerases and the Suppression of Inflammatory and Allergic Responses by Tyrosol from Used Activated Charcoal Waste Generated during Sake Production. J Agric Food Chem. 62(31):7779-86. (共著) 2014/08
論文	Suppression of allergic and inflammatory responses by essential oils derived from herbal plants and citrus fruits. Int J Mol Med.　33(6):1643-51. (共著) 2014/06
論文	Screening of mammalian DNA polymerase inhibitors from rosemary leaves and analysis of the anti-inflammatory and antiallergic effects of the isolated compounds. Food Science and Technology Research 20: 829-40. (共著) 2014/04
論文	Anti-tumor effects of novel 5-O-acyl plumbagins based on the inhibition of mammalian DNA replicative polymerase activity. PLos One 9(2)e88736 (共著) 2014/02
論文	Formosusin A, a novel specific inhibitor of mammalian DNA polymerase β from the fungus Paecilomyces formosus. Bioorg Med. Chem. 22(3): 1070-6. (共著) 2014/02
論文	Inhibition of DNA polymerase λ and associated inflammatory activities of extracts from steamed germinated soybeans. Food Funct. 5:696-704. (共著) 2014/01
論文	Cycloartenyl trans-ferulate, a component of the bran byproduct of sake-brewing rice, inhibits mammalian DNA polymerase and suppresses inflammation. Food Chem. 141(2):1000-7. (共著) 2013/11
論文	Inhibitory effects of a major soy isoflavone, genistein, on human DNA topoisomerase II activity and cancer cell proliferation. Int J Oncol. 43(4):1117-24. (共著) 2013/10
論文	Inhibitory effects of α-mangostin on mammalian DNA polymerase, topoisomerase, and human cancer cell proliferation. Food Chem Toxicol. 59:793-800. (共著) 2013/09
論文	Synthesis, structure, and cytotoxicity studies of some fungal isochromanes. J Nat Prod. 76(9):1737-45. (共著) 2013/09
論文	Inhibitory effects of low molecular weight polyphenolics from Inonotus obliquus on human DNA topoisomerase activity and cancer cell proliferation. Mol Med Rep. 8(2):535-42. (共著) 2013/08
論文	Inhibitory effects of myricetin on mammalian DNA polymerase, topoisomerase and human cancer cell proliferation. Food Chem. 139(1-4):910-8. (共著) 2013/08
論文	Inhibitory effect of novel somatostatin peptide analogues on human cancer cell growth based on the selective inhibition of DNA polymerase β. Bioorg Med Chem. 21(2):403-11. (共著) 2013/01
論文	Effects of essential oils from herbal plants and citrus fruits on DNA polymerase inhibitory, cancer cell growth inhibitory, antiallergic, and antioxidant activities. J Agric Food Chem. 60(45):11343-50. (共著) 2012/10
論文	Antifungal properties of Japanese cedar essential oil from waste wood chips made from used sake barrels. Mol Med Rep. 5(5):1163-8. (共著) 2012/03
論文	Pinophilins A and B, inhibitors of mammalian A-, B-, and Y-family DNA polymerases and human cancer cell proliferation. J Nat Prod. 75(2):135-41. (共著) 2012/02
論文	Inhibition of DNA polymerase λ by glucosyl compounds from soybean (Glycine max L.) and their associated inflammatory activity. Food Chem. 132(4):2046-53. (共著) 2012/01
論文	Dehydroaltenusin is a specific inhibitor of mammalian DNA polymerase α. Expert Opinion on Investigational Drugs　20:1523-34． (共著) 2011/11
論文	DNA polymerase β specific inhibitors, a loliolide derivative and pubinernoid A, isolated from the brown algae Laminaria sp. Letters in Drug Design & Discovery 8(8):671-677 (共著) 2011/10
論文	Inhibitory effect of novel 5-O-acyl juglones on mammalian DNA polymerase activity, cancer cell growth and inflammatory response. Bioorg Med Chem. 19(19):5803-12． (共著) 2011/10
論文	Effects of Intermediates between Vitamins K2 and K3 on Mammalian DNA Polymerase Inhibition and Anti-Inflammatory Activity. Int J Mol Sci. 12(2):1115-32． (共著) 2011/02
論文	Syntheses of Dehydroaltenusin, a Selective Inhibitor of Mammalian DNA Polymerase α. Current Organic Synthesis 8(1):134-44． (共著) 2011/02
論文	Inhibitory effect of somatostatin Peptide analogues on DNApolymerase activity and human cancer cell proliferation. Anticancer Research 30(12):4841-50． (共著) 2010/12
論文	Novel terpenoids, trichoderonic acids A and B isolated from Trichoderma virens, are selective inhibitors of family X DNA polymerases. Biosci Biotechnol Biochem. 74(4):793-801． (共著) 2010/04
論文	Synthesis and structure-activity relationships of dehydroaltenusin derivatives as selective DNA polymerase alpha inhibitors. Bioorg Med Chem. 17(20): 7227-38. (共著) 2009/10
論文	Dehydroaltenusinによる哺乳動物DNAポリメラーゼの阻害作用に関する研究神戸学院大学（学位論文） (単著) 2009/03
論文	The specific inhibitory effect of demethoxydehydroaltenusin, a derivative of dehydroaltenusin, on mammalian DNA polymerase α. Int. J. Mol. Med. 22(6):793-9. (共著) 2008/12
論文	Effect of dehydroaltenusin-C12 derivative on DNA replication in cultured cells. Molecules 13(12):2948-61. (共著) 2008/10
論文	Anti-Tumor Effect of Orally Administered Spinach Glycolipid Fraction on Implanted Cancer Cells, Colon-26, in Mice. Lipids.43(8):741-8. (共著) 2008/08
論文	Inhibitory effects of cholesterol derivatives on DNA polymerase and topoisomerase activities, and human cancer cell growth. Lipids. 43(4):373-82. (共著) 2008/04
論文	Anti-tumor effects of the glycolipids fraction from spinach which inhibited DNA polymerase activity. Nutr Cancer.57(2):216-23. (共著) 2007/06
論文	Nodulisporol and Nodulisporone, novel specific inhibitors of human DNA polymerase lambda from a fungus, Nodulisporium sp. Bioorg Med Chem. 15(9):3109-14. (共著) 2007/05
論文	Cholesterol hemisuccinate: a selective inhibitor of family X DNA polymerases. Biochem Biophys Res Commun. 354(2):619-25. (共著) 2007/03
論文	Anti-tumor effects of dehydroaltenusin, a specific inhibitor of mammalian DNA polymerase α. Biochem Biophys Res Commun. 352(2):390-6. (共著) 2007/01
論文	Inhibitory effect of coenzyme Q on eukaryotic DNA polymerase  and DNA topoisomerase II activities on the growth of a human cancer cell line. Cancer Sci. 97(8):716-23. (共著) 2006/08
論文	Beta – sitosterol – 3 – O - β- D - glucopyranoside: a eukaryotic DNA polymerase λ inhibitor. J Steroid Biochem Mol Biol. 99(2-3):100-7. (共著) 2006/05
論文	Structural analysis of mogrol and its glycosides as inhibitors of animal DNA polymerase and human cancer cell growth. Letters in Drug Design and Discovery 3(4) : 253-60. (共著) 2006/05
論文	Structural relationship of curcumin derivatives binding to the BRCT domain of human DNA polymerase lambda. Genes Cells.11(3):223-35. (共著) 2006/03
論文	5-(Hydroxymethyl)-2-furfural: a selective inhibitor of DNA polymerase lambda and terminal deoxynucleotidyltransferase. Arch Biochem Biophys.446(1):69-76. (共著) 2006/02
論文	Inhibitory effect of tocotrienol on eukaryotic DNA polymerase lambda and angiogenesis. Biochem Biophys Res Commun.339(3):949-55. (共著) 2006/01
論文	Inhibitory effects of glycolipids fraction from spinach on mammalian DNA polymerase activity and human cancer cell proliferation. J Nutr Biochem.16 : 594-601. (共著) 2005/11
論文	Inhibitory effect of dipeptide alcohol derivatives containing mercapto group on eukaryotic DNA polymerase α. Int J Mol Med.16 : 653-9. (共著) 2005/10
論文	Structural analysis of isosteviol and related compounds as DNA polymerase and DNA topoisomerase inhibitors. Life Sci. 77 : 2127-40. (共著) 2005/09
論文	Inhibitory effect of conjugated eicosapentaenoic acid on human DNA topoisomerase I and II. Arch Biochem Biophys.435(1): 197-206. (共著) 2005/08
論文	Structural analysis of catechin derivatives as mammalian DNA polymerase inhibitors. Biochem Biophys Res Comm.333 : 101-9. (共著) 2005/07
論文	Structural analysis of epolactaene derivatives as DNA polymerase inhibitors and anti-inflammatory compounds. Int J Mole Med.15 : 785-93. (共著) 2005/05
論文	Dipeptide alcohol-based inhibitors of eukaryotic DNA polymerase α. Bioorg Med Chem.13 : 2187-96. (共著) 2005/03
論文	Effect of DNA polymerases inhibitory and antitumor activities of lipase-hydrolyzed glycolipids fraction from spinach. J Nutr Biochem. 16 : 121-28. (共著) 2005/02
論文	Novel topoisomerase I and II inhibitors, parameritannins A-2 and A-3, are selective human cancer cytotoxins. Int J Pharm.1 : 138-51. (共著) 2005/02
論文	Inhibitory action of conjugated C18-fatty acids on DNA polymerases and DNA topoisomerases. Lipids39 : 977-83. (共著) 2004/10
論文	The effects of dehydroaltenusin, a novel mammalian DNA polymerase  inhibitor, on cell proliferation and cell cycle progression. Biochim Biophys Acta. 1674 193-99. (共著) 2004/09
論文	Pseudodeflectusin, a novel isochroman derivative from Aspergillus pseudodeflectus a parasite of the sea weed, Sargassum fusiform, as a selective human cancer cytotoxin. Bioorg Med Chem.14 : 3539-43. (共著) 2004/05
論文	A novel DNA topoisomerase inhibitor: dehydroebriconic acid, one of the lanostane-type triterpene acids from Poria cocos. Cancer Sci.95 : 354-60. (共著) 2004/04
論文	L-Homoserylaminoethanol, a novel dipeptide alcohol inhibitor of eukaryotic DNA polymerase from a plant cultured cells, Nicotina tabacum L. Bioorg Med Chem.12 : 957-62. (共著) 2004/03
論文	Pyridoxal 5'-phosphate is a selective inhibitor in vivo of DNA polymerase α and ε Biochem Biophys Res Comm.312: 1025-32. (共著) 2003/12
その他	ウコン属植物ガジュツ-糖代謝改善を基盤とした新たな抗肥満素材としての提案- 2020年度研究助成金研究成果報告書 (共著) 2021/10